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Methods to Help Immune Cells Identify Cancer Cells Found Health Articles | November 21, 2018
Recently, scientists have shown that macrophages have an amazing killing effect on cancer in preclinical models. If the study can be repeated in humans, it will undoubtedly add a powerful new army to cancer immunotherapy.
The immune cells in the human body are an army that fights pathogens. Whether it is a virus, a bacterium Cheap Juwan Howard Jersey , or a parasite, immune cells can effectively attack most invaders and protect us from disease.
In recent years, scientists have discovered a new application of immune cells—treating cancer. Cancer cells often carry a large number of breakthroughs that may be recognized by immune cells. In order to escape the attack of immune cells, these cancer cells have evolved a series of strategies to disguise themselves as good people.
But these tricks have been gradually seen by scientists. By inhibiting the PD-1PD-L1 pathway, we can let immune T cells polish their eyes and attack cancer cells. In addition, we can also separate T cells from cancer patients, insert molecules that recognize cancer cells Cheap Gilbert Arenas Jersey , and then return them to the patient to kill cancer cells.
These treatments using immune cells have achieved remarkable results and have rewritten many treatments for cancer. But scientists also pointed out that the current immunotherapy is concentrated on T cells, slightly monotonous. Be aware that there are many types of immune cells. It would be better if these immune cells can be developed into anti-cancer therapies.
Recently, a study published in Nature Biomedical Engineering, brings us the hope of the emergence of innovative immunotherapy. In this study, scientists have shown that macrophages have an amazing killing effect on cancer in preclinical models.
As the name suggests, macrophages have a "good appetite" that can phagocytose cell debris Cheap Isaiah Thomas Jersey , foreign germs, and other pathogens. Although some studies have shown that macrophages can "eat" cancer cells, why can't they clean the cancer cells when the cancer is just sprouting, and eliminate the disease?
For more than 100 years, as people's understanding of biology has deepened, we have gradually discovered the reason behind it: in our body, there is indeed a group of macrophages with anticancer activity called M1 macrophages. However Cheap Bradley Beal Jersey , tumors can secrete macrophage colony-stimulating factor (MCSF), "buy" these M1 cells, and turn them into M2 macrophages that turing blind eyes to cancer cells.
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